CBD or cannabinoids have received a sufficient amount of attention over the last few years. One particular area that has sparked plenty of interest among medical researchers, users, and also the general public is the effect of cannabinoids on our metabolism.
Its immediate cousin, THC has produced very clear metabolic effects, like increasing appetite, but what about CBD? Can CBD too affect our metabolism? Let us discuss this issue briefly in this short article.
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Can CBD affect your metabolism?
Several studies have proved that CBD can affect the metabolism of our body in several indirect ways. Korean researchers in 2016 have published an important study that explored the CBD effect on “fat browning”.
Unlike white fat, brown fat has been shown that it can help in burning calories and energy, and most probably can also help with weight loss. On the other hand, white fat is believed to increase the risk of heart disease, diabetes, and more.
Another study, published explored whether CBD can help to turn the accumulated white body fat into brown, and thus can serve as an agent in the obesity treatment.
This study found that CBD can have 3 major effects on our fat stores.
- CBD can stimulate genes and protein, which is involved in augmenting the fat breakdown.
- CBD helps in increasing the number of mitochondria and also their activity, subsequently improving our body’s ability to burn energy.
- CBD reduced the expression of specific protein that are involved in creating new fat cells in our body.
Based on the above results, the authors concluded that CBD can convert white fat into brown fat.
How is CBD metabolized?
Based on how CBD is administered, its dose is metabolism will be affected. CBD can be consumed in several ways and the route of administration will also determine your rate of absorption and also pharmacokinetics of CBD.
You can get different oral CBD products like pills, capsules, and edibles, which are absorbed upon ingestion, by the digestive system, and then from the stomach, it enters the liver. Here, it undergoes metabolism and forms metabolites.
After chronic oral administration, the mean half-life of CBD is 2-5 days, which means their effects may last longer.
Through smoking or vaporization CBD is inhaled. It will be heated to a certain temperature, and the vapors formed are inhaled to absorb CBD in the lungs. Here CBD will be immediately getting into the bloodstream from the lungs.
Another effective method is by administering CBD in the sublingual method where the drug is held for 60 seconds under the tongue and swallowed. It will enter the bloodstream through your tiny blood vessels under your tongue.
- Topical and transdermal patches:
Here the application of CBD is through the skin ointment. Transdermal patches placed on your skin surface may release very small amount of CBD that can penetrate skin layers to reach the bloodstream.